Rebiopsy Results of the Patients in Which the First Biopsy Revealed High Grade Prostatic Intraepithelial Neoplasia

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High-Grade Prostatic Intraepithelial Neoplasia

High-grade prostatic intraepithelial neoplasia (HGPIN) has been established as a precursor to prostatic adenocarcinoma. HGPIN shares many morphological, genetic, and molecular signatures with prostate cancer. Its predictive value for the development of future adenocarcinoma during the prostate-specific antigen screening era has decreased, mostly owing to the increase in prostate biopsy cores. N...

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Current significance of the finding of high grade prostatic intraepithelial neoplasia in the prostate biopsy.

INTRODUCTION High grade prostatic intraepithelial neoplasia (HGPIN) is regarded as a precursor of prostate cancer (PC). However, its relationship to cancer has changed throughout the literature, being currently poorly defined and remains controversial for urologists in their clinical practice. Because of his frequency and the impact on patient outcomes that the lack of consensus clinical attitu...

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Frequency of high-grade prostatic intraepithelial neoplasia in Mexican population.

BACKGROUND High-grade intraepithelial neoplasia (HGPIN) is the only lesion regarded as precursor of prostatic carcinoma, though its frequency is unknown in many countries. Here we studied the frequency of HGPIN in a population with high grade frequency of prostatic carcinoma. MATERIAL AND METHODS A total of 486 cases of sextant prostatic biopsies performed from January 2001 to January 2006 we...

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Significance of Atypical Small Acinar Proliferation and High-Grade Prostatic Intraepithelial Neoplasia in Prostate Biopsy

PURPOSE In clinical practice, atypical small acinar proliferation (ASAP) and high-grade prostatic intraepithelial neoplasia (HGPIN) are two common findings on prostate biopsies. Knowing the frequency of a prostate cancer diagnosis on repeat biopsies would aid primary treating physicians regarding their decisions in suspicious cases. MATERIALS AND METHODS One hundred forty-three patients in wh...

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Prostate cancer after initial high-grade prostatic intraepithelial neoplasia and benign prostate biopsy.

INTRODUCTION Limited data exist on long term pathological outcomes in patients with initial prostate biopsies showing either high-grade intraepithelial neoplasia (HGPIN) or benign findings, who are subsequently diagnosed with prostate cancer. MATERIALS AND METHODS Preoperative characteristics of patients showing either HGPIN or benign initial prostate biopsies were investigated and compared i...

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ژورنال

عنوان ژورنال: Üroonkoloji Bülteni

سال: 2016

ISSN: 2147-2270

DOI: 10.4274/uob.630